Ability of Post-treatment Glycyrrhizic Acid to Mitigate Cerebral Ischemia/Reperfusion Injury in Diabetic Mice
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منابع مشابه
Treatment of Hematological Malignancies with Glycyrrhizic Acid.
The current study examined the effectiveness of glycyrrhizic acid (GA) in reducing cell viability and inducing apoptosis in human chronic myeloid leukemia (CML) in vitro and a mouse lymphoma in vivo. Additionally, we assessed GA as a candidate for combinational therapy in CML along with the current frontline treatment, imatinib (IM). Treatment of K562 CML cells with GA alone resulted in signifi...
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Diabetic nephropathy (DN) is a major cause of end-stage renal disease (ESRD). Glycyrrhizic acid (GA) is an effective inhibitor of reactive oxygen species (ROS) production. We investigated the role of GA in the progression of renal injury in DN. Albumin (Alb)/creatinine (crea) levels were significantly lower, and renal histopathology was attenuated in the diabetic db/db mice that were treated wi...
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Glycyrrhizic acid (GA) is a triterpene glycoside found in the roots of licorice plants (Glycyrrhiza glabra). GA is the most important active ingredient in the licorice root, and possesses a wide range of pharmacological and biological activities. GA coupled with glycyrrhetinic acid and 18-beta-glycyrrhetic acid was developed in China or Japan as an anti-inflammatory, antiviral, and antiallergic...
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Introduction: Cardiac preconditioning represents the most potent and consistently reproducible method of rescuing heart tissue from undergoing irreversible ischemic damage. The aim of the present study was to evaluate oxytocin (OT) induced cardioprotection and its signaling pathways on lactate dehydrogenase (LDH) and creatine kinase-MB isoenzyme (CK-MB) in the anesthetized rats. Methods: Ei...
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This study investigates the comparative anti-diabetic activity of glycyrrhizic acid and gymnemic acid on non-insulin dependent diabetic models i.e. oral glucose tolerance (OGTT), adrenalin and dexamethasone induced diabetes. Glycyrrhizic acid and gymnemic acid were isolated from crude extract of Glycyrrhiza glabra and Gymnema sylvestre and authenticated by co -TLC with standard. Invivo antidiab...
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ژورنال
عنوان ژورنال: Medical Science Monitor
سال: 2020
ISSN: 1643-3750
DOI: 10.12659/msm.926551